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Gingival Epithelial Cell Transcriptional Responses to Pathogenic Oral Microbial Species.

  • By: tabukov@subio
  • Date: 2010-05-13 19:09:01
  • Tags:

GEO Series GSE9723
http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE9723
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=Pubmed&term=15888084[UID]

SSA file is available:
https://www.sugarsync.com/pf/D664412_133640_291994

Summary
Transcriptional profiling was utilized to define the biological pathways of gingival epithelial cells modulated by co-culture with the oral pathogenic Porphyromonas gingivalis and Aggregatibacter (formerly actinobacillus) actinomycetemcomitans.
We used microarrays to detail the global programme of gene expression underlying infection and identified distinct classes of up- and down-regulated genes during this process.

Platforms: Affymetrix Human Genome U133A Array (22,283 genes)
#Samples: 12

Please see a moview for instruction of importing SSA files.
http://www.screencast.com/t/OTM2MDE1YTg

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