SNPs in MicroRNAs for Risk Prediction
- By: tabukov@subio
- Date: 2010-02-03 09:00:18
Predicting whether or not cancer patients will develop another primary tumor or experience a relapse is a tricky business. University of Texas MD Anderson Cancer Center's Xifeng Wu and her colleagues have found 18 SNPs in microRNA biogenesis genes and miRNA binding sites that are associated with an increased risk of head and neck cancer patients developing a second primary tumor, or relapsing.
Their results could pave the way for better risk prediction models for head and neck cancer patients. Furthermore, they say their findings could eventually lead to improved risk prediction models for other cancers, including leukemia, breast, and lung, in which there is already evidence implicating the miRNA pathway.
http://www.genomeweb.com//node/932478?hq_e=el&hq_m=608186&hq_l=7&hq_v=98ac932396
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