Transcriptome of the Nxnl1-/- mouse retina
- By: tayac@subio
- Date: 2010-01-26 10:00:35
Series GSE13869 in GEO is now available to see on Subio Platform by importing ssa file from;
https://www.sugarsync.com/pf/D664412_76_8681244332
Summary
Rod-derived Cone Viability Factor (RdCVF, alias nxnl1) is a retina-specific protein identified for its therapeutic potential in supporting cone survival during retinal degeneration.
A nxnl1 knockout mouse model was created and the transcriptome used to demonstrate that the retina is compromised by the absence of nxnl1.
Contributor(s) Cronin T, Raffelsberger W, Lee-Rivera I, Kinzel B, Clerin E, Poch O, Sahel J, Leveillard T
Also see Retinobase. （ref; http://www.biomedcentral.com/content/pdf/1471-2164-9-208.pdf）
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