Lifestyle effect on human gene expression.
- By: tabukov@subio
- Date: 2009-12-08 09:13:35
Researchers from the US, Australia, and Morocco used microarrays to look at expression patterns in leukocytes from around 200 Arab and Amazigh individuals in southern Morocco. They found that lifestyle — particularly whether individuals lived in a city or a rural village — played a larger role in the detected gene expression than either gender or ancestry. The team also identified hundreds of SNPs correlating with gene expression across the group.
http://www.genomeweb.com//node/928779?hq_e=el&hq_m=567747&hq_l=1&hq_v=98ac932396
http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.495.html
Study Suggests Non-Genetic Factors are Better Type 2 Diabetes Risk Predictors than Genetics
As part of the larger Whitehall II prospective cohort study, researchers from the University College London followed thousands of individuals in London's Whitehall district over roughly 20 years. When they looked specifically at factors affecting type 2 diabetes risk, they found that two non-genetic risk models were better predictors of diabetes risk than a genetic model based on nearly two dozen risk alleles.
http://www.genomeweb.com//node/931552?hq_e=el&hq_m=597431&hq_l=1&hq_v=98ac932396